RCVS Specialist in Equine Internal Medicine, Donnington Grove Veterinary Group, Newbury, RG14 2JB
Equine metabolic syndrome (EMS) is a collection of risk factors for endocrinopathic laminitis that consist of obesity, regional adiposity and insulin dysregulation (ID). Adipose tissue dysregulation...
A variety of metabolic derangements can result in neurological dysfunction, which can be reversed by correcting the imbalance in many cases. It should be noted that, since these abnormalities...
Ciclesonide is a glucocorticoid prodrug that is registered for treatment of allergic rhinitis and asthma in humans. It is de-esterified in the lungs to desisobutyryl-ciclesonide, which has a 12 times...
Mammalian kidneys have considerable reserve capacity. Loss of concentrating ability does not typically occur until two thirds of nephron function has been lost, and nitrogenous waste accumulation does...
Lymphoma displays no explicit age bias and cases have been reported in fetuses (Haley and Spraker, 1983) through to geriatrics. However, specific forms of the disease have been anecdotally reported to...
Equine multinodular pulmonary fibrosis (EMPF) is a chronic, progressive, interstitial lung disease of adult horses that has a guarded to poor prognosis. Human idiopathic pulmonary fibrosis (IPF) is a...
In a retrospective study in Vet Surg (2021; 50:323–335. 10.1111/vsu.13564 ) the authors aimed to identify etiology and other findings in horses with peritonitis and report factors associated with...
Within the UK, differences in case numbers of atypical myopathy (AM) and survival rates are present in different locations. Dunkel et al (Equine Vet Ed 2020; 32(2):90-95) hypothesized that admission...
Despite an appropriate diagnostic approach, a causative agent is not identified in many cases of liver disease, and treatment must be guided by clinical signs and biopsy findings. Even biopsy changes...
The equine liver comprises 1.5% of body weight (Dyce et al, 2002) and contains up to 10% of the total blood volume at any one time. It has multiple functions including metabolism of proteins,...
Equine gastric ulcer disease is a cause of morbidity in horses, with an incidence reported at greater than 80%. Wei Le San (WLS) is a Chinese herbal formula of nine herbs selected for putative...